SYNTHESES OF AMINO AND CYANODEOXY SUGARS VIA EPOXY SUGAR INTERMEDIATES AND PHYTOCHEMICAL STUDIES OF SAPONARIA VACCARIA AND PLUMERIA RUBRA

Abstract

This thesis presents the work in three parts. The Part-A describes the syntheses of aminodeoxy sugars (8-15) and cyanodeoxy sugars (16-20) via 2,3-anhydro sugars (1-7). In the reaction sequence region selective trans-diaxial cleavage of oxirane ring in 2,3-anhdro sugars have been affected with trimethyl silyl diethylamine, trimethyl silyl dimethylamine, and trimethyl silyl cyanide. The following new compounds have been obtained…...