I= PHYTOCHEMICAL INVESTIGATIONS OF BLUMEA OBLIQUA
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Title of Thesis
PHYTOCHEMICAL INVESTIGATIONS OF BLUMEA OBLIQUA

Author(s)
Naseer Alam
Institute/University/Department Details
University of Karachi/ H.E.J. Research Institute of Chemistry
Session
1998
Subject
Chemistry
Number of Pages
168
Keywords (Extracted from title, table of contents and abstract of thesis)
blumea obliqua, bithiophenes, acetylenic thiophenes

Abstract
Phytochemical investigations of the aerial parts of Blumea oblique are presented in this thesis. Pet-ether soluble part of the methanolic extract of the aerial parts of Blumea oblique has yielded nine bithiophene acetylenes (85-93). Compounds 85-88 are new natural products. The compound 93 has been mentioned in one of the bohlmann’s papers but no physical or chemical data are available anywhere in the literature. The rest of the bithiophenes are isolated for the first time from blumea oblique. Some known compounds (94-97) have also been isolated, 97 is being reported for the first time from B. Obliqua.

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1373.31 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
73.89 KB
2 1 General Introduction 1
63.36 KB
3 2 Introduction 6
569.99 KB
  2.1 Naturally occurring acetylenic thiophenes and related compounds 6
  2.2 Biosynthesis of naturally occurring thiophenes 12
  2.3 Biological properties of thiophenes acetylenes 39
  2.4 Bithiophene acetylenes in plants 51
  2.5 Literature survey of genus Blumea 62
4 3 Present work 69
525.17 KB
  3.1 Selection of Plant 69
  3.2 Botanical description of Blumea obliqua 70
  3.3 Medicinal significance of Blumea obliqua 71
  3.4 Results and discussion 72
5 4 Experimental 132
170.62 KB
  4.1 General Experimental 132
  4.2 Antimicrobial assays 133
  4.3 Plant material 136
  4.4 Extraction and isolation 136
6 5 References 150
179.75 KB