I= STUDIES ON THE SAPONINS OF GUAIACUM OFFICINALE-L
Pakistan Research Repository Home
 

Title of Thesis
STUDIES ON THE SAPONINS OF GUAIACUM OFFICINALE-L

Author(s)
Iqbal Fatima
Institute/University/Department Details
University of Karachi/ H.E.J. Research Institute of Chemistry
Session
1986
Subject
Chemistry
Number of Pages
150.
Keywords (Extracted from title, table of contents and abstract of thesis)
saponins, guaiacum officinale-l, zygophyllaceae, triterpenoid saponins, guianin a, guaianin a1, guaianin a2, guaianin b-g

Abstract
Guaiacum officinale L. (N.O. Zygophyllaceae) is a medicinal and ornamental plant commonly cultivated in the gardens in Pakistan.

The present thesis describes the isolation of nine new triterpenoid saponins namely guianin A, guaianin A1, guaianin A2, guaianin B-G from Guaiacum officiale L. (N.O. Zygophyllaceae). Two more saponins namely 3-0-[a-L-rhamnopyranosyl]-30-norolean-12,20(29)-dien-28-oic acid and guaianin, have been isolated which were reported earlier from this plant. The structure of guaianin C is proposed and the structures of gaianin A, Guaianin A1, Guainin B, Guaianin D and Guaianin E were determined.These are as follows

1) 3-0-[a-L-Rhamnopyranosyl (1-2)a-L-arabinopyranosyl]-30-norolean-12,20(29)-dien-28-oic acid (Guaianin A) (71).

Download Full Thesis
838.73 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
107.53 KB
2 1 Summary 1
44.46 KB
3 2 General Introduction 7
34.47 KB
4 3 Introduction 12
251.15 KB
  3.1 Pharmacological And Biological Importance Of Saponins 14
  3.2 Pharmacological And Biological Importance Of Guaiacum 17
  3.3 Biosynthesis Of Triterpenoids 41
5 4 Results And Discussion 61
288.57 KB
  4.1 New Nortriterpenoidal Saponins From Guaiacum Officinale 66
  4.2 Unreported Compounds From Guaiacum Officinale 95
  4.3 Reported Compounds From Gauiacum Officinale 101
6 5 Experimental 109
226 KB
  5.1 General Notes 110
  5.2 Plant Material And Extraction And Purification 111
  5.3 Compounds From Guaiacum Officinale 112
7 6 References 141
64.94 KB
8 7 List Of Publications 149
14.83 KB