I= STUDIES ON CHEMICAL CONSTITUENTS ZYGOPHYLLUM PROPINQUUM (Z. COCCINEUM)
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Title of Thesis
STUDIES ON CHEMICAL CONSTITUENTS ZYGOPHYLLUM PROPINQUUM (Z. COCCINEUM)

Author(s)
Ghazala
Institute/University/Department Details
University of Karachi/ H.E.J. Research Institute of Chemistry
Session
1992
Subject
Chemistry
Number of Pages
112
Keywords (Extracted from title, table of contents and abstract of thesis)
zygophyllum propinquum (z. coccineum), saponin constituents, zygophylla-ceae, triterpenoidal saponin

Abstract
The work described in the present thesis is mainly concerned with the isolation and structure elucidation of saponin constituents of Zytgophyllum propinquum (Syn. Z coccineum L.) belonging to the family Zygophylla-ceae. As a result of these investigations five new triterpeniodal saponins have been isolated which were named as zygophyloside A, Zygphyloside B, Zygophloside C, Zygophykloside D and Zygophyloside E, Together with these compound another triterpenoidal saponin, one steroidal saponin and a triterpene ester were also isolated and reported for the first time from this plant. Zyugophyloside D and zygophyloside E were isolated from the column chromatography of the butanolic extract of Zygophyllum propinquum, while the rest of other compounds were isolated from the ethyl acedtate extract of this plant.

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667.3 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents/ Summary
73.81 KB
2 1 General Introduction 6
78.1 KB
3 2 Introduction 12
357.98 KB
  2.1 Saponins 12
  2.2 Biological importance of saponins 12
  2.3 Medicinal uses of saponins 16
  2.4 Biosynthesis of Triterpeniods 17
  2.5 Literature Survey of Genus Zygophyllum 39
4 3 Present work 44
164.8 KB
  3.1 Isolation and structure elucidation of 3-0[B-D- Quinvopyranosyl ]- Quinovic Acid( 55) 46
  3.3 Isolation and Structure Elucidation of Zygophylkoside A (56) 50
  3.4 Isolation and Structure Elucidation of Zygophylkoside B (57) 55
  3.5 Isolation and Structure Elucidation of Zygophylkoside C (58) 61
  3.6 Isolation and Structure Elucidation of Zygophylkoside D (59) 67
  3.7 Isolation and Structure Elucidation of Zygophylkoside E (60) 74
  3.8 Isolation and Structure Elucidation of 3-0-[B-D- Glucopyranosyl ]-B- Sitosterol ( 61) 78
  3.9 Isolation and Structure Elucidation of Erythrodiol-3- caffeate( 62) 83
5 4 Experimental 88
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  4.1 General Instrumentation 88
  4.2 Extraction and Isolation of Saponins 90
  4.3 Characterization of 3-0[B-D- Quinovopyranosyl ]- Quinovic Acid (55) 92
  4.4 Characterization of Zygophyloside A (56) 93
  4.5 Characterization of Zygophyloside B (57) 95
  4.6 Characterization of Zygophyloside B (58) 97
  4.7 Characterization of Zygophyloside B (57) 99
  4.8 Characterization of Zygophyloside B (57) 101
  4.9 Characterization of 3-0-[B-D- Glucopyranosyl ]-B- Sitosterol ( 61) 102
  4.10 Characterization Elucidation of Erythrodiol-3- caffeate( 62) 104
6 5 References 106
89.34 KB