Pakistan Research Repository

ISOLATION AND STRUCTURE ELUCIDATION OF CHEMICAL CONSTITUENTS OF THE BIOLOGICALLY ACTIVE FRANCTIONS OF VERTRUM SPECIES

Sultana, Rahat (1993) ISOLATION AND STRUCTURE ELUCIDATION OF CHEMICAL CONSTITUENTS OF THE BIOLOGICALLY ACTIVE FRANCTIONS OF VERTRUM SPECIES. PhD thesis, University of Karachi, Karachi.

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Abstract

This thesis describes the isolation and structure elucidation of chemical constituents of the biologically active fractions of veratrum album. Chemical and pharmacological investigations of veratrum album have led to the isolation of ten new steroidal alkaloids and invitro antihypertensive testing of three new steroidal bases. Moreover a known steroidal alkaloid have been isolated, the spectral studies on which are reported for the first time. In addition one known steroidal alkaloid previously unreported from Veratrum album is discussed. Their structures were established on the basis of UV, IR, mass spectrometry, and ID 2D and inverse NMR techniques.

Item Type:Thesis (PhD)
Uncontrolled Keywords:vertrum species, alkaloids, steroidal alkaloids, veratrum alkaloids, vertrum album
Subjects:Physical Sciences (f) > Chemistry(f2)
ID Code:904
Deposited By:Mr. Muhammad Asif
Deposited On:14 Nov 2006
Last Modified:04 Oct 2007 21:03

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