I= PHYTOCHEMICAL INVESTIGATIONS ON SOME MEDICINAL PLANTS FROM THE FAMILIES EUPHORBIACEA AND LAMIACEAE
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Title of Thesis
PHYTOCHEMICAL INVESTIGATIONS ON SOME MEDICINAL PLANTS FROM THE FAMILIES EUPHORBIACEA AND LAMIACEAE

Author(s)
Amir Reza Jassbi
Institute/University/Department Details
University of Karachi/ H.E.J. Research Institute of Chemistry
Session
1999
Subject
Chemistry
Number of Pages
205
Keywords (Extracted from title, table of contents and abstract of thesis)
euphorbiacea, lamiaceae, euphorbiacear. euphorbia decipiens boiss. & buhse, euphorbia teheranica boiss., zataria multiflora boiss (lamiaccae)

Abstract
The dissertation describes the characterization of the chemical constituents of two plants of the genus Euphorbia from the family Euphorbiacear. Euphorbia decipiens Boiss. & Buhse and Euphorbia teheranica Boiss., which are endemic to Iran. And the essential oil of Zataria multiflora Boiss (Lamiaccae) from Pakistan.

Investigation of E. decipiens results in five novel diterpenoids with a new parent alcohol skeleton. Named as decipinone (79), isodecipinone (84), decipidone (85), isodecipidone (86) and decipinone A (87), and two noel tetracyclic diterpenoids, decipinol ester A (88) and B(90). Karajinone A(91) and B(94) were identified as two new pentacyclic diterpene esters with a rare carbon skeleton related to lathyrol. The known compounds isolated from this plant included, B-sitosterol (95), cycloeucalenol (96) obtusifoliol (97), cycloart-23-ene-3,25-diol (98), and 24-methylenecycloartan-3B-ol(99).

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S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents/ Summary
111.58 KB
2 1 Introduction 5
408.11 KB
  1.1 The Botantcal specifications of the Genus Euphorbia 5
  1.2 The biological activates and medicinal uses of the Genus Euphorbia 7
  1.3 Classification of Diterpenoids 16
  1.4 Structural types of diterpenoids 18
  1.5 Biosythesis of terpenoids 22
  1.6 Biosynthesis of Diterpenoids 28
  1.7 A Brief Introduction on the Essential oils 44
3 2 Results and Discussion 52
688.68 KB
  2.1 Part A: Phytochemical investigation of Euphorbia decipiens Bioss & Buhse 52
  2.2 Part B: Phytochemical Investigation of Euphorbia teheranica Bioss 99
  2.3 Part C: Constituents of the Essential oil of Zataria Multiflora Bioss 120
4 3 Experimental 127
555.57 KB
  3.1 General Experimental Procedures 127
  3.2 Part A :Phytochemical Investigation of Euphorbia Decipiens 129
  3.3 Part B: Phytochemical Investigation of Euphrbia Tehranica 152
  3.4 Part C :Chemical investigation of the essential oil Zataria Multiflora 162
  3.5 Appendix A: X-Ray Crytallographic Data for decipinone (79) 178
  3.6 Appendix B: X-ray Crytallographic data for decipinol ester A (88) 184
5 4 References 192
158.16 KB