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PHYTOCHEMICAL AND STRUCTURAL STUDIES ON THE CHEMICAL CONSTITUENTS OF ADHATODA VASICA, SARCOCOCCA SALIGNA AND SKIMMIA LAUREOLA

Sultana, Nighat (2000) PHYTOCHEMICAL AND STRUCTURAL STUDIES ON THE CHEMICAL CONSTITUENTS OF ADHATODA VASICA, SARCOCOCCA SALIGNA AND SKIMMIA LAUREOLA. PhD thesis, University of Karachi, Karachi.

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Abstract

The thesis describes studies on the chemical constuents of Skmmialaureala.Hook Adhotoda vastea Nees and Sarcococca saligna (D.Don) Muel. Studies on the chemical constituents of these plants have lead to the isolation of eleven new quinoline, triterpene and coumarin compounds. In addition eleven known quinzoline, furanoquinline pyranoquinoline and substituted comarine have been detected for the first time from these plants. Modern spectroscopic methods were employed to determine their structures. NEW COMPOUNDS Methoxy-1 methy1-3-(2’-axo-3’ methyl butyl) – 2 quinolone (190) J.Nat Prod,1998 vol 61(6) PP.713, 717 4-Methoxy 1-methyl-3 (2’S-hydroxy-3’ ene butyl) 2-quinolone (206). J Nat Prod 1998 vol 61(6) PP.713-717. Methyl cycloaudenol (215) Nat. Prod. Lett. (submitted) 3-Oxo-lanosta-20,25 diene 3-one (230) Nat Prod. Lett. 1998, 12(3)PP.223-229 7-Methoxy-6(2R-Methoxy-3-hydroxy-3’ methyl butyl)coumarin(239). Nat Prod.Lett (Submitted) 4-Methoxy-1-methyl-3 (2’S-acetoxy-3’ene butyl) 20quinolone (254). J.Nat Prod.1998,61(6)PP.713-717 4-Methoxy-1-methyl-3 (2’S-acetoxy-3’ene butyl) 20quinolone (262). J.Nat Prod.1998,61(6)PP.713-717 Methyl isoplatydesmine (270) Nat Prod Lett. 1998 ,12(3) PP,223-229 3-Hydroxy 2,2,6-trimethyl-3,4,5,6-tetrahydro-2H pyrano(3,2-e) quinoline-5one (277) Heterocycle (submitted) 7-0-B-D-glueopyranoside 2H-1 benzopyran 2-one (282). Heterocycle (submitted) 3a Hydroxy-D-friedoolean-5-ene (317) Nat. Prod.Lett.1997,10(4)PP,249,256. B.KNOWN COMPOUNDS Isogospherol (286) Nat. Prod.Lett.(Submitted) Heraclenol (291). Nat. Prod.Lett.(Submitted) 7-Methoxy-6-(2’oxo-3’methyl butyl) coumarin(295) Nat. Prod.Lett.(Submitted) 5.8-Dimethoxy coumarin-2H-1 benzopyrane-2one (303) Nat. Prod.Lett.(Submitted) Ulopterol(307) Nat. Prod.Lett.(Submitted) Ribalinine (299) Heteracycle(Submitted) Stigmasterol (311) Taraxerol (330) Nat. Prod.Lett.1997-10(4) PP-249-256 Peganidine (334). Nat. Prod.Lett.1997,10(4)PP-249-256 Vasicinone (334) Nat. Prod.Lett.1997,10(4)PP,249-236 Dictamnine (302)

Item Type:Thesis (PhD)
Uncontrolled Keywords:adhatoda vasica, sarcococca saligna, skimmia laureola, skimania laureala hook, sarcococca saligna muell, adhatoda vasica nees, quinzoline, furanoquinline pyranoquinoline, comarine
Subjects:Physical Sciences (f) > Chemistry(f2)
ID Code:861
Deposited By:Mr. Muhammad Asif
Deposited On:01 Nov 2006
Last Modified:04 Oct 2007 21:03

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