I= PHYTOCHEMICAL INVESTIGATIONS ON DURANTA REPENS LINN AND PHYSALIS PERUVIANA LINN
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Title of Thesis
PHYTOCHEMICAL INVESTIGATIONS ON DURANTA REPENS LINN AND PHYSALIS PERUVIANA LINN

Author(s)
Saeed Ahmad
Institute/University/Department Details
University of Karachi/ H.E.J Research Institute of Chemistry
Session
1999
Subject
Number of Pages
233
Keywords (Extracted from title, table of contents and abstract of thesis)
duranta repens linn, physalis peruviana linn, solanaceae, verbenaceae, lupeol (75), betulin (76), β-sitosterol (77), β-sitosterol glucoside (78), stigmasterol (79), stigmasterol glucoside (80), withaphysanolide (59), viscosalactone b (60), withaperuvin f (61), coagulin (62), physalolactone b (63), physalolactone b glucoside (64)

Abstract
The present doctoral thesis describes phytochemical studies on two medicinally important plants of Pakistani origin namely Physalis peruviana Linn and Duranta repens Linn. Phytochemical investigations of Physalis peruviana have resulted in the isolation of eight new compounds (51-58) belonging to withanolide class of natural products.

In addition, six known compounds of the same class have also been isolated for the first time from this plant: withaphysanolide (59), viscosalactone B (60), withaperuvin F (61), coagulin (62), physalolactone B (63) physalolactone B Glucoside (64).

Phytochemical studies on Duranta repens have led to the isolation of a new steroid (74), along with six known compounds: lupeol (75), betulin (76), β-sitosterol (77),β-sitosterol glucoside (78), stigmasterol (79) and stigmasterol glucoside (80).

The identity of new compounds was determined by a combination of spectroscopic data including various 2D NMR experiments and chemical transformations.

Download Full Thesis
1767.31 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
87.2 KB
2 1 Physalis Peruviana 1
1529.14 KB
  1.1 Solanaceae 1
  1.2 Phytochemical Studies on Physalis Peruviana 36
  1.3 Experimental 146
3 2 Duranta Repens 186
259.58 KB
  2.1 Verbenaceae 186
  2.2 Results and Discussion 190
  2.3 Experimental 210
4 3 References 220
121.19 KB
5 4 List of Publications 231
29.14 KB
6 5 Publications Resulted From This Work 233
13.97 KB