Pakistan Research Repository

PHOTOCHEMICAL INVESTIGATIONS OF AJUGA PARVIFLORA BENTH., TRIANTHEMA PORTULACASTRUM LINN. AND PAEONIA EMODIWALL

Nawaz, Hafiz Rub (2000) PHOTOCHEMICAL INVESTIGATIONS OF AJUGA PARVIFLORA BENTH., TRIANTHEMA PORTULACASTRUM LINN. AND PAEONIA EMODIWALL. PhD thesis, University of Karachi, Karachi.

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Abstract

The art of healing has its origin from the antiquity of human civilization. Man as a savage, must have known by experience how to relieve his sufferings by the use of herbs growing around him. The historical survey of traditional medicine reveals that in his search for food the primitive men began to distinguish those pharmacological actions. Thus the drugs from plant origin have served through the ages as the mainstay for the treatment of a variety of ailments and preservation of human health. A large reservoir of platn based medicines has been provided in the early period covering the Indian, Chinese Sumerian, Egyptian Assyrian and Muslim civilizations. In the indo-Pakistan Sub-continent studies in the chemical constituents of indigenous medicina plants have been carried out at various research centers to serve the dual purposes of broadening pharmacopial spectrum and providing a bases for therapeutic study directed towards the syntheses of drugs modeled on chemical structure of natural products. In this contrxt it is a special interest to note that the largest and the most sophisticated nucleus for the systematic investigations in the chemistry of biologically active principals of indigenous medicinal plants is based at Karachi under the name of HEJ Research Institute of Chemistry, which is presently under the directorship of famous plant Chemist of Pakistan Prif. Atta-ur-Rehman. Taking into account the facts stated above the work undertaken for the present doctoral dissertation relates to the isolation and structural studies of new natural products from three indigenous medicinal plants of Pakistan namely Ajuga parviflora Benth., Trianthema portulacastrum Linn. And paeonia emodi wall. The thesis is, therefore, divided into three parts entitiled; Part_A. Phytochemical Investigations of Ajuga Parviflora Benth. Part B. Phytochemical Investigations of Trianthema Protulacastrum Linn. Part C. Phytochemical Investigations of paeonia emodi wall. Part –A: Photochemical Investigations of Ajuga Parviflora Benth. Ajuga parviflora benth belongs to the family Labiatae and has found diverse medicinal uses in indigenous systems of medicine. It has been used as astringent and for the treatment of swollen wounds, diarrhea, rheumatic fever, eye diseases and diseases of bladder [5, 7]. The systematic phytochemical studies on the whole plant material, collected from northern areas of Pakistan, have led to the isolation and the structure elucidation of five new withanolides. Besides, a number of unreported compounds have been isolated and characterized.

Item Type:Thesis (PhD)
Uncontrolled Keywords:ajuga parviflora benth., trianthema portulacastrum linn., paeonia emodiwall, labiatae, aizoaceae, paeoniaceae
Subjects:Physical Sciences (f) > Chemistry(f2)
ID Code:789
Deposited By:Mr. Muhammad Asif
Deposited On:19 Oct 2006
Last Modified:04 Oct 2007 21:02

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