I= STUDIES ON THE CHEMICAL CONSTITUENTS OF PLUCHEA ARGUTA BOISS. AND PLUCHEA LANCEOLATA
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Title of Thesis
STUDIES ON THE CHEMICAL CONSTITUENTS OF PLUCHEA ARGUTA BOISS. AND PLUCHEA LANCEOLATA

Author(s)
Rasheeda Khatoon
Institute/University/Department Details
University of Karachi./ H.E.J Research Institute of Chemistry
Session
1998
Subject
Chemistry
Number of Pages
156
Keywords (Extracted from title, table of contents and abstract of thesis)
pluchea arguta boiss, pluchea lanceolata, terpenoids, eudesmane, genus pluchea

Abstract
Sent thesis is divided into two parts. The first part entitled “Studies on Chemical ents of Pluchea arguta Boiss compositae) describes the isolation and structure on of seven codesmance typesesquierpenes in which five eudesmance sesquiterpenes are se are follows:…

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S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents/Summary
82.63 KB
2 1 Part-A : Studies On Chemical Constitutents Of Pluchea Arguta 5
215.55 KB
3 1 Introduction 6
215.55 KB
  1.1 General Introduction 6
  1.2 Significance Of Natural Products In Organic Chemistry 7
  1.3 The Terpenoids 8
  1.4 Classification And Occurrence Of Terpenoids 12
  1.5 The Sesquiterpenes 16
  1.6 Iosynthesis Of Sesquiterpenes 20
  1.7 The Eudesmane 26
  1.8 Biosynthesis Of Eudesmane 26
  1.9 Selection Of Plant 36
4 2 Genus Pluchea 37
195.29 KB
  2.1 Botanical Description Of Pluchea Arguta 37
  2.2 Medicinal Importance Of Pluchea 38
  2.3 Literature Review Of Pluchea 40
5 3 Present Work 69
377.01 KB
  3.1 4,5-Epicryptomerinol (1) Structure Elucidation 69
  3.2 Pluchargutin (2) Structure Elucidation 76
  3.3 4-Acetoxy-3, 4-Di-Epi-3-Choro-2-Hydroxy-Arguticinin (3) Structure Elucidation 85
  3.4 4-Acetoxy-3,4-Di-Epi-Odonticinin (4) Structureelucidation 94
  3.5 4-Acetoxy-3-Chloro-2-Hydroxy-3-Epi-Arguticinin (6) Structure Elucidation 102
  3.6 4-Acetoxy-3-Chloro-2-Hydroxy-4-Epi-Arguticinin (6) Structure Elucidation 109
  3.7 4-Acetoxy-3-Chloro-2-Hydroxy Arguticinin (7) Structure Elucidation 112
  3.8 3.8a-Taraxasteryl Acetate (8)-Structure Elucidation 115
6 4 Experimental 118
240.51 KB
  4.1 General Note 118
  4.2 Plant Material 119
  4.3 Method Of Extraction And Isolation 120
  4.4 Crude Sesquiterpenic Mixture 120
  4.5 Isolation And Characterization Of 4,5-Epi-Cryptomeridiol (1) 4,5(A) Biological Activity Of (1) 122
  4.6 Isolation And Characterization Of Pluchargutin (2) 4,6 (A) Biological Activity Of (2) 124
  4.7 Isolation And Characterization Of 4-Acetoxy-3,4-Di-Epi-3-Chloro-2-Hydroxy Arguticinin (3)4,7 (A) Biological Acitivity Of (3) 126
  4.8 Isolation And Characterization Of 3,4-Di-Epi-Odonticinin (4) 128
  4.9 Isolation And Characterization Of 4-Actoxy-3-Chloro-2-Hydroxy-3-Epi-Arguticinin (5) 130
  4.10 Isolation And Characterization Of 4-Acetoxy-3-Chloro-2-Hydroxy-4-Epi-Arguticinin 132
  4.11 Isolation And Characterization Of 4-Actoxy-3-Chloro-2-Hydroxy Arguticinin (7) 134
  4.12 Isolation And Characterization Of A-Taraxasteryl Acetate 136
7 5 Part-B : Studies On Chemical Constitutenis Of Pluichea Lanceolata 138
77.06 KB
  5.1 Introduction 138
  5.2 Experimental 145
8 6 References 148
97.2 KB
  6.1 List Of Publications 156