I= STUDIES ON CHEMICAL CONSTITUENTS OF INULA GRANTIOIDES AND CAPPARIS DECIDUA
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Title of Thesis
STUDIES ON CHEMICAL CONSTITUENTS OF INULA GRANTIOIDES AND CAPPARIS DECIDUA

Author(s)
Nargis Ismail
Institute/University/Department Details
University of Karachi/Department of Education
Session
1991
Subject
Chemistry
Number of Pages
183.
Keywords (Extracted from title, table of contents and abstract of thesis)
inula grantioides, capparis decidua, crude alkalids, inula grantioides, flavonoids

Abstract
Part-A

This thesis in divided into two parts. Part-A describes the isolation and structural studies of three novel flavones from inula grantioides Boiss. In addition, eight other known compounds have also been isolated for the first time from this plant, they are; a sesquiterpene, two known flavones, three triterpenes, a sterol and its glycoside.

w Compounds

1. Grantiodin Phytochemistry, 30 1040 (1991). 2.Nrantionin Z. Natruforsch 46b, 950-954 (1991). 3.Grantiodinin Z. Natruforsch 46b, 950-954 (1991). II.Known compounds unreported from Inula grantioides Pluchidione Z. Natruforsch 46b, 950-954 (1991). 2.5,7-dihydroxy-6,4-dimethoxyflavone 3.5-hydroxy,6,7,4-trimethoxyflavone (manuscript under preparation) Lupeol taraxasterol taraxasterol acetate B-Sitosterol (Phytochemistry, 30, 1040 (1991). Sitosteryl B-D-glucoside (manscript under preparation)

Part B
of this thesis deals with the isolation and structure elucidation of two new spermidine alkaloids from Capparis deciduas (Forssk.) Edgew. Spermidine alkaloids are macrocyclic alkaloids containing, hydroxylated, methoxylated, trains cinnamic acid residues which are linked to each other through oxygen bridge and to spermidine, through amide bonds. These type of compounds may exist in two region isomeric forms with respect to spermidine moiety. Their structure can only be confirmed by X-rays crystallography or through mass spectral fragmentation pattern.

1. New alkaloids

1. Isocodonocarpine Phytochemistry, 28 2493 (1989) 14-N-acetyl isocodonocarpine (manuscript under preparation).

Download Full Thesis
1037.76 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
48.39 KB
2 1 General Introduction 3
22.41 KB
3 2 Introduction 6
295.17 KB
  2.1 Flavonoids 7
  2.2 Classification of Flavonoids 8
  2.3 Biosynthesis of flavonoids 16
  2.4 Botanical Description of Inula grantioides 33
  2.5 Medicinal and commercial importance of Inula 33
  2.6 Literature Review 36
4 3 Present Work (Results and discussion) 50
226.53 KB
  3.1 New Flavonoids 51
  3.2 Known compounds unreported from Inula Grantioides 70
5 4 Experimental 88
128.37 KB
  4.1 General Notes 89
  4.2 Plant Material 91
  4.3 Extraction and isolation of crude flavonoids 91
  4.4 Compounds from Inula grantioides (except flowers) 91
6 5 Introduction 106
179.9 KB
  5.1 Alkaloids as remedy 107
  5.2 Classification of alkaloids 108
  5.3 Spermidine alkaloids 110
  5.4 Occurrence and biosynthesis of spermidine Alkaloids 115
  5.5 Botanical description of capparis deciduas 122
  5.6 Medicinal and commercial Importance of Capparis 124
  5.7 Literature Review 126
7 6 Present work (Results and Discussion) 134
215.04 KB
  6.1 Alkaloids 135
8 7 Experimental 165
57.85 KB
  7.1 Plant material 166
  7.2 Extration and isolation of crude alkalids 166
  7.3 Compounds from Capparis deciduas 166
9 8 References 172
78.49 KB
10 9 List of Publications 182
14.07 KB