I= SOLATION AND CHARACTERISATION OF CHEMICAL CONSTITUENTS OF ERBERIS ARISTATA, FAGONIA INDICA (F. CRETICA) AND DAUCUS CAROTA
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Title of Thesis
SOLATION AND CHARACTERISATION OF CHEMICAL CONSTITUENTS OF ERBERIS ARISTATA, FAGONIA INDICA (F. CRETICA) AND DAUCUS CAROTA

Author(s)
Akbar Ali Ansari.
Institute/University/Department Details
University of Karachi./H.E.J Research Institute of Chemistry
Session
1983
Subject
Chemistry
Number of Pages
156.
Keywords (Extracted from title, table of contents and abstract of thesis)
erberis aristata, fagonia indica (f. cretica), daucus carota, karachine, taxilamine, pseudobenzylisoquinoline alkaloid

Abstract
The work described in this thesis relates to detailed chemical investigations carried out on Berberis aristata and fagonia indica as well as some preliminary studies undertaken on Daucus carota. These studies have resulted in the isolation of 21 different compounds, 5 of which were found to be new.

The first chapter of thesis deals with the isolation and structure elucidation of six different alkaloids from Berberis aristata. Two of these named “Karachine” and “Taxilamine” were found to be new. “Karachine” is the most complex of more than fifty protoberberine alkaloids presently known and is the first naturally occurring berbinoid incorporating acetone units. “Taxilamine” is a pseudobenzylisoquinoline alkaloid and it is fourth member of this family.

The second chapter of the thesis deals with the isolation and structure elucidation of eight different compounds from Fagonia indica. A new sapogenin named “Nahagenin” has been isolated and its structure and identified as 28-0-B-D-glucopyranosyl-3-0-B-D-glucopyranosyl hederagenin and 28-0-B-D-glucopyranosyl glucopyranosyl-3-0-B-D-glucopyranosyl hederagenin. The last chapter of the thesis deals with isolation and preliminary structural studies on the chemical constituents of Daucus carota from which seven different compound have been isolated.

Download Full Thesis
1044.17 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
40.65 KB
2 1 Biosynthesis 1
149.65 KB
  1.1 Biosynthesis of isoquinoline alkaloids 1
  1.2 Biosynthesis of triterpenoids 22
3 2 Isolation and structural studies on Berberis aristata 31
394.49 KB
  2.1 Introduction 31
  2.2 Results and Discussion 45
  2.3 Experimental 65
4 3 Isolation and structural on Fagonia indica 76
439.82 KB
  3.1 Introduction 76
  3.2 Results and Discussion 84
  3.3 Experimental 107
5 4 Isolation and structural studies on Daucus carota 134
73.17 KB
  4.1 Introduction 134
  4.2 Results and Discussion 139
  4.3 Experimental 141
6 5 References 144
135.93 KB
  5.1 Publications 157