Shah, Zahir (1990) STUDIES ON THE CHEMICAL CONSTITUENTS OF STOKEYIA INDICA, ERVATAMIA CORONARIA AND HAPLOPHYLLUM SPECIES. PhD thesis, University of Karachi, Karachi.
The thesis is divided into four parts. Part-A describes studies on the chemical constituents of Haplophyllum burbaumii. Investigation on the stem bark of H. buxbaumii has led to the isolation of five new ligan glucosides: Part-B describes studies on the chemical constituents of Stokeyia indica. Investigation on S. judica has led to the isolation and structure elucidation of a novel linear metabolite (stokerine, 11), besides loliolide (12) and fucosterol (13) isolated for the first time from this brown alga. Part-C describes studies on the chemical constituents of Ervatamia coronaria. Investigation on the twigs of E. coronaria has led to the isolation of the following compounds. Part-D of the thesis contains the Experimental section, and is followed b the References. Modern spectroscopic techniques including 2D NMR experiments (2D-J-resolved, COSY-45, NOESY, NOE, HeteroCOSY, SECSY) were employed and chemical transformations were carried out to establish the structures of the above mentioned compounds. The stereochemistry was established by extensive NOE difference measurements. Temperature dependent 1H-NMR studies were carried out to gain insight into the conformational equilibria existing in compounds (3), (5) and (10).
|Item Type:||Thesis (PhD)|
|Uncontrolled Keywords:||stokeyia indica, ervatamia coronaria, haplophyllum, lignans, haplophyllum buxbaumii.|
|Subjects:||Physical Sciences (f) > Chemistry(f2)|
|Deposited By:||Mr. Muhammad Asif|
|Deposited On:||27 Sep 2006|
|Last Modified:||04 Oct 2007 21:02|
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