I= ISOLATION AND STRUCTURAL STUDIES IN THE CHEMICAL CONSTITUENTS OF SALVIA MOORCROFTIANA AND EUPHORBIA DECEPINES Title of Thesis


Pakistan Research Repository

 

 

 

 

 

 

Title of Thesis

ISOLATION AND STRUCTURAL STUDIES IN THE CHEMICAL CONSTITUENTS OF SALVIA MOORCROFTIANA AND EUPHORBIA DECEPINES

Author(s)

Muhammad Asim

Institute/University/Department Details

University of Karachi, Karachi

Session

2002

Subject

Chemistry

Number of Pages

175

 

Keywords (Extracted from title, table of contents and abstract of thesis)

Salva Moorcroftiana, Euphorbia Decipiens, Flavonoids, Benzoic Acid, Terpenoids, Flavonoid glycosides, B-Amyrin, 15-Deoxyfuerastione, Erythrodiol, Luteolin-7-Methyl Ether, 5-Hydroxy-4, 7-Dimethoxy Flavone, Apigenin, Stigmasterol Glucoside, B-Sitosterol, Apigenin-7-O-B-D-Glucoside, 13-Deacetylisodecipinone, Decipidone, Decipidone Ester A, Decipidone Ester B

 

Abstract

The work embodied in this thesis is divided into two parts. In Part-A the chemical investigation of Salvia moorcroftiana is described. Part-B deals with the chemical investigation of Euphorbia decipiens, which belongs to the genus Euphorbiaceae. The structure elucidation of all isolated compounds described in part A and B were carried out by using various spectroscopic techniques including 1H-NMR, 13C-NMR, DEPT, HMQC, HMBC, COSY-45°, nOe, EI, CI, FD, -ve and +ve FABMS, IR and UV.

PART –A Isolation and Structural Studies in the Chemical Constituents of Salvia moorcroftiana:

The work on Salvia moorcroftiana has resulted in the isolation and characterization of six new constituents. Out of these four compounds contain flavonoid glycosides skeleton and two are benzene derivatives. In addition to new constituents, nine known compounds have also been isolated and characterized from this species. The new constituents isolated from Salvia moorcroftiana are: Genkwanin-4-O-rhamnosylgalactoside (10), Genkwanin-4-O-arabinosylgalactoside (11), Genkwanin-4-O-dirhamnosylgalactoside (12), Genkwanin-4-O-arabinosyl-rhamnoside (15), Nonyl-4-hydroxy-benzoate (13) and Moorcroftianoside (14). The known compounds isolated from Salvia moorcroftiana are: B-Amyrin (1) 15-Deoxyfuerastione (2), Erythrodiol (3), Luteolin-7-Methyl Ether (4), 5-hydroxy-4, 7-dimethoxy flavone (5), Apigenin (6), Stigmasterol Glucoside (8), B-Sitosterol Glucoside (7) and Apigenin-7-O-B-D-Glucoside (9).

PART –B Isolation and Structural Studies in the Chemical Constituents of Euphorbia decipiens

Part-B deals with the isolation and characterization of chemical constituents from Euphorbia decipiens, a species of the genus Euphorbiaceae. The compounds isolated from this species includes: 13-Deacetylisodecipidone (1), 13-Deacetylisodecipinone (2), Decipidone (3), Decipinol ester A (4) and Decipinol ester B (5).

 

Download Full Thesis

180.kbs

1537 KB

 

S. No. Chapter Title of the Chapters

Page

Size (KB)

    Table of Contents  

180.kbs
61 KB

    Glossary  

180.kbs
38 KB

    Summary  

180.kbs
46 KB

PART - A

1 1 INTRODUCTION 4

180.kbs
227 KB

       
2 2 RESULTS AND DISCUSSION 34

180.kbs

395 KB

       
3 3 EXPERIMENTAL 80

180.kbs

162 KB

       
4 REFERENCES 101

180.kbs

93 KB

       

PART - B

5 1 INTRODUCTION

112

180.kbs

267 KB

6 2 PRESENT WORK

143

180.kbs

190 KB

7 3 EXPERIMENTAL

163

180.kbs

57 KB

8   REFERENCES

170

180.kbs

50 KB