ISOLATION AND STRUCTURE ELUCIDATION OF CHEMICAL CONSTITUENTS OF THE BIOLOGICALLY ACTIVE FRANCTIONS OF VERTRUM SPECIES

Rahat Sultana, . (1993) ISOLATION AND STRUCTURE ELUCIDATION OF CHEMICAL CONSTITUENTS OF THE BIOLOGICALLY ACTIVE FRANCTIONS OF VERTRUM SPECIES. Doctoral thesis, University of Karachi.

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Abstract

This thesis describes the isolation and structure elucidation of chemical constituents of the biologically active fractions of veratrum album. Chemical and pharmacological investigations of veratrum album have led to the isolation of ten new steroidal alkaloids and invitro antihypertensive testing of three new steroidal bases. Moreover a known steroidal alkaloid have been isolated, the spectral studies on which are reported for the first time. In addition one known steroidal alkaloid previously unreported from Veratrum album is discussed. Their structures were established on the basis of UV, IR, mass spectrometry, and ID 2D and inverse NMR techniques.

Item Type: Thesis (Doctoral)
Uncontrolled Keywords: vertrum species, alkaloids, steroidal alkaloids, veratrum alkaloids, vertrum album
Subjects: Q Science > QD Chemistry
Depositing User: Ms Maryam Saeed
Date Deposited: 27 Jul 2017 10:31
Last Modified: 27 Jul 2017 10:31
URI: http://eprints.hec.gov.pk/id/eprint/4114

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