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Title of Thesis

Hepatitis C Virus Persistence: Virus and Host Related Factors

Author (s)
Aneela Yasmeen
Institute/University/Department Details
Aga Khan University, Karachi
Session
2005
Subject
Bio Chemistry
Number of Pages
182
Keywords (Extracted from title, table of contents and abstract of thesis)
 

Abstract


2869 KB

S. No. Chapter Title of the Chapters Page Size (KB)
  0    
1 1 Hepatitis C virus: an overview 1
  1.1 Introduction 1
  1.2 Genomic organization 1
  1.3 Geographical distribution of HCV genotypes 2
356 KB
  1.4 Epidemiology 5
  1.5 Current strategies 20
 
2 2 Phylogenetic Analysis of HCV Isolates in Pakistan  
  2.1 Introduction 25

621 KB

 

  2.2 HCV Genotypes 25
  2.3 Hypothesis 39
  2.4. Aims 39
  2.5 Materials and Methods 40
  2.6 Results 47
  2.7 Discussion 58
3 3 HCV IRES Translation Efficiency  
  3.1 Introduction 61
  3.2 Virus Related Factors 61


1104 KB

  3.3 Hypothesis 71
  3.4 Aims 71
  3.5 Material and Methods 72
  3.6 Results 83
4 4 Host related Factors in Viral Persistence  
388 KB

 

 

 

  

  4.1 Introduction 101
  4.2 Host-Virus Interaction 101
  4.3 Hypothesis 106
  4.4 Aims 106
  4.5 Material and Methods 107
  4.6 Results 109
  4.7 Discussion 117
  4.8 Host Immune Status 119
  4.9 Hypothesis 125
  4.10 Aims 125
  4.11 Materials and Methods 126
  4.12 Results 131

 

42 KB

167 KB

  4.13 Discussion 135
5 5 Conclusion 138
       
       
6 6 Bibliography  140