I= EVALUATION OF AZOBENZENE, BENZYLIDENE-ANILINE AND THEIR DERIVATIVES AS CHELATING ORGANIC REAGENTS
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Title of Thesis
EVALUATION OF AZOBENZENE, BENZYLIDENE-ANILINE AND THEIR DERIVATIVES AS CHELATING ORGANIC REAGENTS
Author(s)
Asad Gulzar
Institute/University/Department Details
Institute of Chemistry/ University of the Punjab
Session
1993
Subject
Chemistry
Number of Pages
192
Keywords (Extracted from title, table of contents and abstract of thesis)
azobenzene, benzylidene-aniline, organic reagents, agrobacterium tumefaciens, pseudomonas aerogenosa, pseduomonas putida, bacillus subtilis, bacillus thruingiensis, corynebacterium petrophilum, ascochyta rabiei

Abstract
In order to understand the behaviour of various azo-compounds and Schiff bases like p-aminoazobenene, diazoaminobenzene, p-nitrobenzene-azo-salicylic acid (sod slat) {2-[4-(dimethyl-amino) phenyl-azo] benzoic acid}, benzylidene-aniline, o-hydroxy benzylidene-p-tolidene, m-hydroxy-benzylidene aniline, p-hydroxy benzylidene-aniline, o-methoxy-benzylindene-aniline with different transition metal cations. E.g Cu++, Ag+, Au++, Zn++, Cd++, Hg++, Ni++, Pd++, Pt++ and Co++, the complexes were synthesized. The stoichiometric method of continuous variation. The stability constants of these metal complexes were also calculated by the same method.

The complexes were characterized by the metal analysis. The thermal stabilities of chelates were determined by thermal gravimetric and differential thermal analysis(TGA/DTA) techniques. The antibacterial and antifungal activities of chelates were tested against Agrobacterium tumefaciens (25,24) Pseudomonas aerogenosa (2556), Pseduomonas putida (2569), Bacillus subtilis, Bacillus thruingiensis, Corynebacterium petrophilum (2513) and Ascochyta rabiei (isolate NA-5) by Agar well plate method
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2226.48 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
112.4 KB
2 1 Introduction
58.33 KB
  1.1 General Introduction 1
  1.2 Biological Medicinal Importance of Transition Metals 2-4
  1.3 Importance of Chelates as Medicinal Agents 4
3 2 Literature survey
149.99 KB
  2.1 General 5
  2.2 Stability constants 8
  2.3 Thermal Stability 10
  2.4 Antimicrobial Activity 10
4 3 Experimental
493.4 KB
  3.1 Materials and methods 16
  3.2 Instruments 17
  3.3 Synthesis of Ligands 21
  3.4 Table 3.1 (UV/VIS-Spectra of Ligands ) 24
  3.5 Table 3.2 (Infrared spectra of ligands ) 25
  3.6 Reactions of Ligands with Transition Metal Compounds 27
  3.7 Analytical Evaluation of complexes 42
  3.8 Atomic Absorption Spectroscopy 42
  3.9 Table 3.4 (Analytical data of complexes 48
  3.10 Table 3.5 (Infrared spectra of complexes ) 50
  3.11 Results and discussion 55
5 4 Stability constants
395.21 KB
  4.1 Stability of complexes 56
  4.2 Stability constants 56
  4.3 Determination of Stability constants Jobā€™s Methods of Variation 57
  4.4 Experimental 58
  4.5 Procedure 58
  4.6 Tables( 4.1-4.20) 60
  4.7 Results and discussion Figures( 4.1-4.20) 80
6 5 Thermogravietric and differential thermal analysis( TGA/DTA) 82
212.59 KB
  5.1 Results and discussion Figures (5.1-5.20) 82
7 6 Antimicrobial activity of chelates of AZO compounds Schiff bases 91
780.88 KB
  6.1 Assay for antibacterial activity by the Agar well plate method 91
  6.2 Assay for Antifungal activity by the Agar well plate method 92
  6.3 Table (6.1-6.9) 93
  6.4 Results and discussion 102
  6.5 Antibacterial activity 102
  6.6 Antifungal Activity 103
  6.7 Conclusion 103
  6.8 Summary 105
  6.9 References 106