| |
Title of Thesis
BIOAVAILABILITY AND DISPOSITION KINETICS OF ERYTHROMYCIN IN NORMAL, FEBRILE, METABOLICALLY ALTERED AND WATER DEPRIVED RABBITS |
Author(s)
Mahmood Ahmad |
Institute/University/Department Details
University Of Punjab Lahore |
Session
1990 |
Subject
Pharmacy |
Number of Pages
165 |
Keywords (Extracted from title, table of contents and abstract of thesis)
ERYTHROMYCIN, Serum Protein Binding, Febrile Condition, Diabetic Condition, Dehydration State, WATER DEPRIVED RABBITS |
Abstract
|
 |
 |
 |
 |
 |
| S. No. |
Chapter |
Title of the Chapters |
Page |
Size (KB) |
 |
 |
 |
 |
 |
| 1 |
0 |
Content |
|
 130.16 KB |
 |
 |
 |
 |
 |
| 2 |
1 |
Introduction |
1 |
 27.8 KB |
 |
 |
 |
 |
 |
| 3 |
2 |
Review Of Literature |
4 |
 204.24 KB |
| |
2.1 |
Bioavailability/Disposition Kinetics Of Erythromycin |
4 |
| |
2.2 |
Dissolution And Degradation |
4 |
| |
2.3 |
Absorption |
5 |
| |
|
Serum Protein Binding |
7 |
| |
|
Distribution In Body Tissues And Fluids |
8 |
| |
2.6 |
Elimination |
11 |
| |
2.7 |
Metabolism |
14 |
| |
2.8 |
Elimination Half-Life |
15 |
| |
2.9 |
Febrile Condition |
16 |
| |
2.10 |
Diabetic State |
18 |
| |
2.11 |
Dehydration Condition |
20 |
 |
 |
 |
 |
 |
| 4 |
3. |
Materials And Methods |
26 |
 204.24 KB |
| |
3.1 |
Chemicals And Regents |
26 |
| |
3.2 |
Materials |
27 |
| |
3.3 |
Instrumentation |
28 |
| |
3.4 |
Experimental Protocol |
29 |
| |
3.5 |
Production Of Experimental Conditions |
30 |
| |
3.6 |
Drug Administration |
31 |
| |
3.7 |
Sampling Procedure |
32 |
| |
3.8 |
Body Weight, Packed Cell Volume And Biochemical Analysis |
34 |
| |
3.9 |
Analysis Of Erythromycin |
36 |
| |
3.10 |
Pharmacokinetic Computation |
38 |
| |
3.11 |
Statistical Analysis |
39 |
 |
 |
 |
 |
 |
| 5 |
4 |
Result |
40 |
 197.13 KB |
| |
4.1 |
Group 1-Febrile Condition |
40 |
| |
4.2 |
Group Ii-Diabetic Condition |
52 |
| |
4.3 |
Group Iii-Dehydration State |
63 |
 |
 |
 |
 |
 |
| 6 |
5 |
Discussion |
73 |
 164.85 KB |
| |
5.1 |
Group I-Febrile Condition |
73 |
| |
5.2 |
Group Ii-Diabetic Condition |
78 |
| |
5.3 |
Group Iii-Dehydration Condition |
84 |
 |
 |
 |
 |
 |
| 7 |
6 |
Summary And Conclusions |
87 |
 20.58 KB |
 |
 |
 |
 |
 |
| 8 |
7 |
Reference |
90 |
 217.53 KB |
 |
 |
 |
 |
 |
| 9 |
8 |
Appendices |
110 |
 101.9 KB |
 |
 |
 |
 |
 |