Pakistan Research Repository


Muhammad, Obaid-ur-Rahman (1995) A STUDY ON FETO-PLACENTAL HEALTH IN KARACHI WOMEN. PhD thesis, University of Karachi, Karachi.



n the present work a study of the evaluation of fetoplacental health in Karachi women has been made. One thousand pregnant women were selected from different parts of Karachi. During this study hematological, clinical, biochemical evaluations and ultrasonic scanning carried out. On the basis of our results, it is concluded that Down’s syndrome (0.20%), Rhesus affected pregnancy (2.22%) and pregnancy induce hypertension (37.20%) rates are slightly high. Maternal diabetes (9.20%), intrauterine growth restriction (9.00%) and congenital malformation (0.80%) rates are higher. Fetal alcohol syndrome (0.10%), drug addiction (2.00%) during pregnancy and twin pregnancy is very low but the fetal mortality and morbidity is very high The high rates are due to poor availability of medical facilities and less education of pregnant females in Pakistan and the rate is very low due to poor care, restriction of government and religious factor. If the medical, educational and other facilities are increases or enhanced in Pakistan, the neonatal and perinatal mortality and morbidity can be much reduced The overall result of outcome of pregnancy in Karachi women is evaluated it is concluded that rate of Down’s syndrome is nearly same as in the other parts of the world, incidences of Rhesus affected pregnancy is slightly higher because of lack of awareness and immunoprophylaxis, incidences of pregnancy induce hypertension is same as in other parts of the world but maternal and fetal outcome is very bad it is due to lack of antenatal care and poor medical facilities, in twin pregnancy the incidence is 21 twin pregnancies per thousand pregnancies, rate of complications perinatal mortality and morbidity is much higher due to poor pediatric care facilities, incidences of congenital malformation is slightly higher than the western world, the reason being very high rate of consanguous marriages, infectious and injudictious intake of drugs pregnancy which is mainly due to illiteracy, fetal alcohol syndrome, drug addiction during pregnancy are rarest in our study. While these are the leading causes of prenatal mortality and morbidity in the west. The reason of this difference is, Pakistan is a Muslim country and alcohol is prohibited in Islam moreover there is government band on liquor as well It is therefore, concluded that major factors which effect fetal and maternal health are poor rate of literacy, lack of awareness and poor availability of medical facilities. If the literacy rate and medical facilities are improved then both maternal and feral mortality and morbidity rate can be much reduced

Item Type:Thesis (PhD)
Uncontrolled Keywords:feto-placental health, karachi women, pregnant women, down’s syndrome, rhesus, hypertension, maternal diabetes, intrauterine growth restriction, congenital malformation, fetal alcohol syndrome, drug addiction, twin pregnancy, fetal mortality, morbidity, cord blood cortisol, fetal hemoglobin, erythrocytes, leukocytes
Subjects:Biological & Medical Sciences (c) > Medical Sciences (c2) > Pharmacy(c2.5)
ID Code:1403
Deposited By:Mr. Muhammad Asif
Deposited On:26 Feb 2007
Last Modified:04 Oct 2007 21:06

Repository Staff Only: item control page