I= PHYSIOLOGIC AND BIOCHEMICAL CHANGES IN DEHYDRATION AND ITS EFFECT PHARMACOKINETIC OF ACETAMINOPHEN
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Title of Thesis
PHYSIOLOGIC AND BIOCHEMICAL CHANGES IN DEHYDRATION AND ITS EFFECT PHARMACOKINETIC OF ACETAMINOPHEN

Author(s)
Tasneem Ahmad
Institute/University/Department Details
Department of Pharmaceutics/ University of Karachi
Session
1985
Subject
Number of Pages
128
Keywords (Extracted from title, table of contents and abstract of thesis)
acetaminophen, water deprivation, dehydration

Abstract
No Abstract

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869.6 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents
65.26 KB
2 1 Literature Review 1
162.4 KB
  1.1 Introduction 2
  1.2 Physiologic And Biochemical Changes In Dehydration 5
  1.3 Effect Of Water Deprivation On Pharmacokinetics 14
  1.4 Acetaminophen 16
3 2 Experimental 24
142.06 KB
  2.1 Materials And Apparatus 25
  2.2 Human Experimental Protocol 29
  2.3 Analysis Of Acetmatinophen And Its Two Major Metabolites In Blood And Urine 34
  2.4 Biochemical Analysis 37
  2.5 Pharmacokinetic Computation 41
  2.6 Statistical Analysis 43
4 3 Results And Discussion 44
403.87 KB
  3.1 Physiologic And Biochemical Changes 45
  3.2 Effect Of Dehydration On Pharmacokinetics Of Acetaminophen In Humans 69
5 4 Summary And Conclusion 101
106.95 KB
6 5 Bibliography 113
151.79 KB