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| Pakistan Research Repository | Home |
Title of Thesis |
| Author(s) Tasneem Ahmad |
| Institute/University/Department Details Department of Pharmaceutics/ University of Karachi |
| Session 1985 |
| Subject |
| Number of Pages 128 |
| Keywords (Extracted from title, table of contents and abstract of thesis) acetaminophen, water deprivation, dehydration |
Abstract |
| Download Full Thesis |  869.6 KB |
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| S. No. | Chapter | Title of the Chapters | Page | Size (KB) |
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| 1 | 0 | Contents | 65.26 KB |
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| 2 | 1 | Literature Review | 1 | 162.4 KB |
| 1.1 | Introduction | 2 | ||
| 1.2 | Physiologic And Biochemical Changes In Dehydration | 5 | ||
| 1.3 | Effect Of Water Deprivation On Pharmacokinetics | 14 | ||
| 1.4 | Acetaminophen | 16 | ||
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| 3 | 2 | Experimental | 24 | 142.06 KB |
| 2.1 | Materials And Apparatus | 25 | ||
| 2.2 | Human Experimental Protocol | 29 | ||
| 2.3 | Analysis Of Acetmatinophen And Its Two Major Metabolites In Blood And Urine | 34 | ||
| 2.4 | Biochemical Analysis | 37 | ||
| 2.5 | Pharmacokinetic Computation | 41 | ||
| 2.6 | Statistical Analysis | 43 | ||
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| 4 | 3 | Results And Discussion | 44 | 403.87 KB |
| 3.1 | Physiologic And Biochemical Changes | 45 | ||
| 3.2 | Effect Of Dehydration On Pharmacokinetics Of Acetaminophen In Humans | 69 | ||
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| 5 | 4 | Summary And Conclusion | 101 | 106.95 KB |
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| 6 | 5 | Bibliography | 113 | 151.79 KB |
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