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| Pakistan Research Repository | Home |
Title of Thesis |
| Author(s) Pir Muhammad |
| Institute/University/Department Details University of Karachi/ H.E.J Research Institute of Chemistry |
| Session 1999 |
| Subject Chemistry |
| Number of Pages 201 |
| Keywords (Extracted from title, table of contents and abstract of thesis) ajuga parviflora, paeonia emodi, a. parviflora, withanolides |
Abstract Phytochemical studies on the whole plant of A. parviflora have led to the isolation of fourteen compounds. Among these compounds eight are new while the remaining six are new source compounds. The new compounds are, 4-acetyloxy-4-(methylenecarboethoxy)-cyclohexa-2, 5-dienone (51), 4-acetyloxy-4-(methylenecarboethoxy)-cyclohexa-2, 5-dienone (52), 4-hydroxy-4-(methylenecarboethoxy)-cyclohexa-2, 5-dienone (53), Ajugin A (60), Ajugin B (61), Ajugin C (62) and Ajugin D (63). The new source source compounds are, 4-hydroxy-4-(methylenecarboethoxy)-cyclohexa-2, 5-dienone (54), β-sitosterol (55), stigmast-erol (56), lupeol (57) oleanolic acid (58) and ajugalactone (64) Fitoterapia 1999 70, 229. Fitoterapia 1999, 70, 229. Fitoterapia 1999 70, 229.Phytochemistry 1999, 51, 669. J. Nat. Prod. 1999, 62, 1290. J. Nat. Prod. 1999, 62, 1920. Helv. Chim. Act. 1999, 82, 1423. Helv. Chim.. Act. 1999, 82, 1423 Studies on the chemical constituents of Paeonia emodi resulted eight compounds. Among these compounds two monoterpene glyxosides Wurdin (65) and Benzoyl wurdin (66) are new, the Lactiflorin (67), Galloyoxypaeoniflorin (68), 1,5-dihydroxy-3-methylanthraquinone (69) Methyl grevillate (70), Ethyl gallate (71) are new source compounds while Paeoniflorin (72) is know compkound The structures of these know and known natural products were determined on the basis of extensive spectroscopy including one-and two- and inverse two-dimensional NMR experiments (like COSY and HMQC) and chemical derivatizations Z.fut Naturforschung 1999, 54b, 544, Z. Fur Naturforschung 1999, 54b, 544. |
| Download Full Thesis |  1546.91 KB |
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| S. No. | Chapter | Title of the Chapters | Page | Size (KB) |
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| 1 | 0 | Contents | 0 | 89.55 KB |
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| 2 | 1 | Ajuga Parviflota | 1 | 1170.61 KB |
| 1.1 | Pharmacological Importance Of Genus Ajuga | 9 | ||
| 1.2 | Introduction To Withanolides | 11 | ||
| 1.3 | Phytochemical Studies On Ajuga Parviflora | 45 | ||
| 1.4 | New Withanolides From Ajuga Parviflora | 71 | ||
| 1.5 | Experimental | 118 | ||
| 1.6 | Determination Of Antimicrobial Activity | 119 | ||
| 1.7 | Plant Material | 120 | ||
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| 3 | 2 | Paeonia Emodi | 142 | 368.1 KB |
| 2.1 | New Compounds From Paeonia Emodi | 148 | ||
| 2.2 | Phytochemical Study On Paeonia Emodi | 147 | ||
| 2.3 | Unreported Compounds From Paeonia Emodi | 162 | ||
| 2.4 | Reported Compound From Paeonia Emodi | 172 | ||
| 2.5 | Experimental | 174 | ||
| 2.6 | Plant Material | 174 | ||
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| 4 | 3 | References | 187 | 119.28 KB |
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| 5 | 4 | List Of Publications | 199 | 25.98 KB |
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| 6 | 5 | Publications Resulted From This Work | 201 | 13.77 KB |
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