I= STUDIES ON THE CHEMICAL CONSTITUENTS OF RHAZYA STRICTA, MITERAGYNA PARVIFOLLIA AND WITHANIA SOMNIFERA
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Title of Thesis
STUDIES ON THE CHEMICAL CONSTITUENTS OF RHAZYA STRICTA, MITERAGYNA PARVIFOLLIA AND WITHANIA SOMNIFERA

Author(s)
Samina Abbas
Institute/University/Department Details
University of Karachi/ H.E.J Research Institute of Chemistry
Session
1995
Subject
Chemistry
Number of Pages
240
Keywords (Extracted from title, table of contents and abstract of thesis)
rhazya stricta, miteragyna parvifollia, withania somnifera, alkaloids, indole alkaloids

Abstract
This thesis presents the work on the chemical constituents of Withania somnifera, Rhazya stricta and Mitragyna Parvifolia. Investigation of each plant is discussed in separate sections

Section-A It describes the studies on the chemical constituents of the whole plant of withania somnifera, the work has led to the isolation of five steroidal lactones, of these five three were new (i, ii, iii,), while the remaining two were reported ones (iv, v),. (i) withasomidienone (ii) sommnifericine (Heterocycles in press) (iii) 2,3-Dehydrosomnifericine (Heterocycles, in press) (iv) 2,3-Dihyehowithaferin-A (v) 27-Dehydrosywithefericine-A

Section-B It deals with the investigations on the roots of Rhazya stricta. Seven indole alkaloids were isolated, out of which three were new (I, ii, iii), one was new from the genus Rhazya (iv), while remaining three were already reported from this plant (i) Saifine (Nat. Prod. Lett, 1995, 5, pp245-253) (ii) Saifinine (iii) Isosaifinine (iv) Pseudoyohimbine (v) Strictanol (vi) 15, 20, 15’, 20’-Tetrahydrosecamine (vii) 16R, 16’-Decarbomethoxytetrahydrosecamine

Section-C It describes the isolation of six compounds from the stem bark of Mitragyna parvifolia. Three of them were found new from the genus Mitragyna (I, ii, iii) while remaining three were reported ones (iv, v, vi). (i) Scopoletin (ii) Thermophyllin (iii) Daucosterol (iv) Quinovic acid (v) Mitraphyllin (vi)β-Sitosterol

Download Full Thesis
1408.74 KB
S. No. Chapter Title of the Chapters Page Size (KB)
1 0 Contents 0
83.17 KB
2 1 Section-A-1 Withania Somnifera 6
734.85 KB
  1.1 Introduction 6
  1.2 Biosynthesis 21
  1.3 Results And Discussion 33
  1.4 Experimental 87
  1.5 References 98
3 2 Section-B-2 Rhazya Stricta 109
609.97 KB
  2.1 Introduction 109
  2.2 Alkaloids 113
  2.3 Results And Discussion 132
  2.4 Experimental 180
  2.5 References 193
4 3 Section-C-3 Mitragyna Parvifolia 202
223.32 KB
  3.1 Introduction 202
  3.2 Results And Discussion 204
  3.3 Experimental 227
5 4 References 237
33.86 KB
  4.1 List of Publications 240