Pakistan Research Repository

PHYTOCHEMICAL INVESTIGATION ON THE CHEMICAL CONSTITUENTS OF PAEONIA EMODI WALL, ALYSICARPUS MONOLIFER LINN. AND AJUDA BRACTEOSA WALL

Riaz, Naheed (2004) PHYTOCHEMICAL INVESTIGATION ON THE CHEMICAL CONSTITUENTS OF PAEONIA EMODI WALL, ALYSICARPUS MONOLIFER LINN. AND AJUDA BRACTEOSA WALL. PhD thesis, University of Karachi, Karachi.

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Abstract

God has gifted Pakistan with enormous varieties of medicinal plants. Out of these only 20% have so far been evaluated for their therapeutic potentials. Therefore, there is a need of coordinated and well-organized efforts in the area of chemistry of indigenous medicinal plants. The H.E.J. Research Institute of Chemistry is one of the most sophisticated and advanced centre of the world fro plant chemistry. It was initially established by well-known senior scientist of Pakistan late Prof. Salimuzzaman Siddiqui. After him the institute has been ably served by reknowned Pakistani Scientist Prof. Atta-ur-Rahman. The institute has state of art facilities for bioassay directed studies on medicinal plants. The present Ph. D. thesis deals with the pharmacochemical studies on three indigenous medicinal plants of Pakistan namely Paeonia emodi, Alysicarpus monolifer and Ajuga bracteosa. The thesis is, therefore presented in the following three parts: Part-A : Phytochemical Investigations on the Chemical constituents of paeonia emodi wall. Paeonia emodi wall. (Paeonianceae) occurs in the northern areas of Pakistan at high altitude. Various Paeonia species including Paeonia emodi wall. are used as anticoagulant, emmenaguge, anticoagulant and in the treatment of scarlet fever, haemorrhage, bilious obstructions, dropsy, epilepsy and hysteria [1-4] Phytochemical studies on the ethanolic extracts of roots and fruits of P. emodi, elucidation of five new and thirteen known compounds. Part-B:Phytochemical investigations on the Chemical constituents of Alysicarpus monolifer Linn. Alysicarpus monolifer Linn. Belongs to the family Papilionacease. The plant has been sued in indigenous system of medicine for the treatment of leprosy, cough, purgative, anti-pyretic, stomach pain and expectorant properties [3,4]. Phytochemical studies on the whole plant material, collected from Karachi (Pakistan), have resulted in the isolation and structure elucidation of a new triterpenoid of oleane series named as alysional. In addition five known compounds have also been isolated for the first time from this species. Part-C:Phytochemical investigations on the Chemical constituents of Ajuga bracteosa wall.Ajuga bracteosa wall. belongs to the family Labiatae and has found diverse medicinal uses in the indigenous systems, of medicine. It has been used as bladder[1-3]. The systematic phytochemical studies on the whole plant material, collected from Swat (Pakistan), have led to the isolation and structure elucidation of three new withanolides. Beside, a number of unreported compounds have been isolated characterized

Item Type:Thesis (PhD)
Uncontrolled Keywords:paeonia emodi wall, alysicarpus monolifer linn., ajuda bracteosa wall, alysional, triterpenoid, oleane, labiatae, withanolides, papilionaceae, genus alysicarpus
Subjects:Physical Sciences (f) > Chemistry(f2)
ID Code:1170
Deposited By:Mr. Muhammad Asif
Deposited On:03 Jan 2007
Last Modified:04 Oct 2007 21:04

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